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BPT
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Research
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Research topics
Novel biocatalyst
In the presence of cytosolic DNA, the enzyme cyclic GMP-AMP synthase (cGAS) catalyzes the synthesis of the second messenger 2'3'-cyclic GMP-AMP (cGAMP) [1]. The cyclic dinucleotide cGAMP is currently of [...] production of the relevant cyclic dinucleotides. [Translate to English:] [1] Sun, L., et al, Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science (New York …